Autism in Genetic Syndromes

Implications for assessment and intervention

Dr. Jo Moss, Prof. Chris Oliver and Galina Ignatova, The Cerebra Centre for Neurodevelopmental Disorders, University of Birmingham.

This research summary has been prepared to help parents and carers of children with genetic syndromes understand how and why autism or related characteristics might occur in children with genetic syndromes and what this might mean for assessment and intervention related to these characteristics in this population. This research summary provides a review of information that has been presented in peer reviewed scientific articles and reviews, (1,2,3). This research summary was updated in March 2019 following a review of relevant literature published since the research summary was originally printed in 2013.

1. Moss, J. and Howlin, P. (2009). Invited Annotation – Autism spectrum disorders in genetic syndromes: Implications for diagnosis, intervention and understanding the wider ASD population. Journal of Intellectual Disability Research, 53, 852-872.

2. Moss, J., Howlin, P and Oliver, C. (2011). The assessment and presentation of Autism Spectrum Disorder and associated characteristics in individuals with severe intellectual disability and genetic syndromes. The Oxford Handbook of Intellectual Disability and Development. Editors: Jake Burack, Robert Hodapp, Grace Iarocci and Edward Zigler. New York: Oxford University Press.

3. Richards, C., Jones, C., Groves, L., Moss, J., & Oliver, C. (2015). Prevalence of autism spectrum disorder phenomenology in genetic disorders: a systematic review and meta-analysis. The Lancet Psychiatry, 2(10), 909-916.


Autism in Genetic Syndromes - Cerebra Research Summary
First published 2012. This edition 2022. Review date 2025.

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